I've been biking for 20 years. I pretty much have every car we own set up to support carrying a bike in some minimum fashion, and some of the secondary vehicles have been pretty highly modified to support cycling endeavors.
So let's see....when I bought a cheap mountain bike for campus commuting in college I had a trunk rack ona 1988 Accord Coupe. Functional, but a PITA.
A couple years after college when I actually took that same bike to a trail for the first time and started riding regularly I was driving a 1970 Impala sedan. You could drop the front wheels of 2 bikes and put them in the trunk with the loose wheels and close the lid. Not slick, but well protected.
When I bought the Mustang in 2005 I was trail riding 2x per week after work all year. Initially this mean laying down the back seat and inserting the bike in the trunk. With the front wheel off it fit but just barely. There are still some scratches in the interior trunk trim plastic from it. As soon as Hidden Hitch started making a receiver hitch for the S197 I installed one. I did a brake job for the local bike store mechanic on his crap wagon in exchange for a steel, 2-bike Hollywood receiver hitch rack. This is the kind that has the loops at teh bottom for the wheels and a hook that slides down to lock the bike. Simple, secure. I got a lot of grief for running a bike rack on a then-brand-new Mustang, but that rack has kept the bikes secure through all kind of wild driving, drifting and triple digit speeds. I also found that the weight of 2 bikes makes it hook on a hard launch like nobody's business. The mustang was my daily for years and as such my default bike hauler since I rode directly after work. The only down side to this is that over the years the driver's seat bolster at the front has been steadily eaten by the bug repellent on my leg when I slid in. Or at least that's my suspicion. It just might be that Ford's red leather isn't the best.
At the same time my wife was driving a much-loved 97 Explorer. I made a flat wood plate that fit just inside the rear hatch with 3 fork traps on it. I had to pull the front wheels (and the seatpost/saddle on my bikes) and put 3 bikes inside with gear. This was a great way to do longer trips because the bikes were secure and out of the weather. It was kind of a PITA to pull them apart, but I liked it in general. It allowed us to tow a pop-up camper while still taking my bike and the dog/s. Eventually I built a roof rack that could put 2 bikes up on fork traps and allow us a lot more cargo room, but bikes in the back with the rear seats down is still probably my favorite set up of any I've had. The truck was a V8, 2wd so it was fun to drive and comfortable, but it was old enough you could throw muddy bikes and sweaty gear in it without worrying. We eventually sold it to buy more towing capacity. I still miss that truck, but it was pushing 275k miles when we let it go.
This is a dark inside shot, loading up for Ididaride in Florida one year:
In '14 we bought the misses her first new car, a Mazda 6, that I immediately put a Hidden Hitch on for bike transport. This is the car that convinced me heated seats were a perfect addition for post ride comfort. this shot is from the 6 Gap century parking lot in Dahlonega GA, may be '15 or '16?
After the Explorer I bought a 96 F250 power stroke with an 8' bed. I welded up a fork rack for the front of the bed. With just an extended cab it really wasn't the best bike vehicle. But it looked cool.
After I sold the F250 I bought a '98 Jeep Grand Cherokee, partially trying to recreate the Explorer magic but with real off road ability. It never lived up to the hype. It came with an ancient Thule fork-trap and tray roof rack, so I ran with it. I also tried to set up the interior fork trap that I'd used on the Explorer, but the cargo area was just enough smaller that it just never worked well. It was just too short, both in height and length.
Also, I had to work on it so much I never got to ride....So I sold it....
and finally bought a new-ish pickup that's my daily driver instead of a backup vehicle. Now the Mustang is the backup, sunny day fun car. And it doesn't have to haul bikes anymore (but sometimes it still likes to.)
The F150 is 2013 4dr, short bed. Right now I've got fork traps mounted just behind the rear window on top of the box where the hard tonneau rolls up. This means the bikes sit up taller than the cab, but it's the only way to fit them inside the bed with the tailgate up.
If the bed was the 6'5" instead of 5'5", I could put a fork trap inside the tailgate and it would fit inside, but the truck is already the same wheelbase as the F250, I don't really want it longer. I sometimes still use the old hitch rack on the truck if I'm traveling with lots of cargo, and it works great but you can't lower the tailgate. I think the perfect option would be one of the roll up hard tonneaus that has tracks to mount crossbar towers, that way I could rack mount the bikes above the tonneau while still hauling safe cargo. If I didn't hate camper shells so much I'd remove the tonneau cover (and it's box) so the bike would fit inside the bed, then go to a high-top camper shell with opening side panels. But that would cost about $3000 and i HATE camper shells most of the time. They're always in the way and they look stupid.
On the other hand, the truck is so comfortable and spacious that it makes a pretty good support vehicle. The back seat area is so big that I can fold up 2/3 of the seat and use it as a changing room in bad weather. Plus, if I'm really worried about the bike being outside, I can fold the seat all the way up and fit the bike in the cab.