I'm 50, and just into the bottom of "overweight" where I've sat since I was... 35? 6', 190lb. I was 155-160 from 19-35. I don't know how much was age, and how much was that this was shortly after I got into a relationship with my now wife, transitioned from going back to school to full time software developer, had money to eat out...
The last time I made good headway on doing a bit better, the biggest change I made was to stop eating as soon as I was full. I love food, I eat quickly, and I tend to eat whatever I put on my plate, refill it if I'm not noticeably full, and let restaurants pick my portion size (restaurant portion sizes are generally massive).
This relative success (got down steadily and without flailing to about 180; I would say that my ideal is probably 170-175; 160 was *skinny*) came in coordination with a period of consistent exercise. Consistency has always been the hardest part for me. I think there may be vagaries, but a lot of it comes down to running a caloric deficit to lose weight, and it's easy to overestimate how many calories exercise burns. I think exercise is important to feeling good and being healthy, but as noted above, it won't make up for too many calories.
Skipping from weight to aches, the surprise win from that consistency borne out of following a training plan (Systm, formerly Sufferfest, for cycling) was that it came with 3-4 15-minute yoga sessions a week. I had never, ever considered yoga, as it was all too "woo woo" for me. The accompanying sessions were straightforward, did not talk to me about chakras or spirit guides, and I suddenly realized a month in that I was no longer limping and shuffling across the yard when I took the dog out in the morning. I hadn't noticed that I just failed to hurt.
Last item: If you have anything musculoskeletal that's bugging you specifically as opposed to a general achiness, see a physical therapist. They can figure out what's wrong, what exercises will fix it, and you can do them intensively to undo the pain, and then fold them in every now and then as maintenance. I've had pretty good luck with a book called Pain Free by Peter Egoscue, but mostly used it for exercises to un-crick my neck... other stuff I go see someone who knows enough to actually diagnose the underlying issues; it's not always intuitive even if it is logical. I've had shoulder, back, hip flexor stuff that I tried to rest and limp along with for months and a PT was able to sort each out relatively quickly (though certainly not instantly).